Microbiological studies in the development of wound healing ointment

Aim. To select the concentration of fennel essential oil as an antimicrobial component and amaranth antioxidant in composition a wound healing ointment for therapy second third phases process. Materials methods. The study objects were model samples with lipophilic extract marigold, oil. antibacterial antifungal activity was determined experiments vitro by agar diffusion method. properties performed biotesting on biological Paramecium caudatum infusoria grown Lozin-Lozinsky nutrient medium at temperature 20-26 °С. results statistically processed using Excel Windows software. Results discussion. studies conducted showed presence action varying degrees all different concentrations There slow increase ointments promising providing maximum effect 1.5 % 2.0 %. Taking into account slight difference growth retardation zones requirements safety cost-effectiveness chosen further research. Exposure experimental led to prolongation period under influence poisons compared control, indicating high level activity. Conclusions. Based microbiological biotesting, components (fennel – %, 8 %) has been substantiated when developing